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Part Two-Breast Cancer -What can be done to reduce your risk?

Part Two-Breast Cancer -What can be done to reduce your risk?

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Enhance Elimination of Toxic Estrogen Metabolites

Phase 2 detoxification involves methylation and glucuronidation to enhance elimination and inactivate toxic estrogen metabolites. Phase 2 detoxification requires many important enzymatic pathways (sometimes affected by gene mutations) and nutrients such as vitamin B6, B12 folic acid, magnesium, glyceine, as well as a healthy working gastrointestinal tract. Fatty acid balance and mitochondrial function are critical to these processes and can be optimized through nutritional supplements such as omega 3 (DHA/EPA) and co-enzyme Q 10 found in femMED Heart Health.

Decrease Aromatase Activity

After menopause, the ovaries no longer produce estrogen (E2). Instead, post- menopausal estrogen is converted from androgens by an enzyme called, aromatase predominantly in fat tissue. Fat derived “estrone” is a potent stimulator of breast tissue and tightly binds to estrogen receptors. It is strongly associated with breast cancer. Losing weight decreases estrone production. Aromatase activity is inhibited by flax, green tea extract (EGCG), vitamin C, chrysin and flavinoids. Prescription medications such as letrozole also block this enzyme.

Dr. Jennifer Pearlman
Dr. Jennifer Pearlman is a medical doctor with a focused practice in the area of women’s health and wellness.

She is a NAMS Certified Menopause Practitioner certified by the North American Menopause Society (NAMS) and is attending staff physician at the Menopause Clinic at Mount Sinai Hospital in Toronto. Dr. Pearlman has been awarded a focus practice designation by the Ontario Medical Association to enable her to work as an expert consultant to other physicians in the area of women’s health.

Dr. Pearlman completed her medical school and residency training at The University of Toronto. She graduated with Honours and received numerous scholarships and awards.

Dr. Pearlman is an active member of the Canadian and Ontario Medical Associations, the College of Physicians and Surgeons of Ontario, and the College of Family Physicians of Canada. She is an active member of the North American Menopause Society (NAMS) and the American Academy of Anti-Aging Medicine (A4M) and is completing a Fellowship in Anti-Aging Regenerative Medicine (FAARM).

Dr. Pearlman is passionate, approachable, caring and committed to enhancing the life of midlife women. Offering the best of both conventional and integrative approaches, Dr. Pearlman helps her patients achieve optimal health and wellbeing.

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